Abstract Search

ea0041gp223 | Thyroid Cancer | ECE2016

Macro, but not micrometastases, detected by OSNA technique are related with more aggressive papillary thyroid cancer features

Zafon Carles , Iglesias Carmela , Gonzalez Oscar , Temprana Jordi , Caubet Enric , Garcia-Burillo Amparo , Obiols Gabriel , Serres Xavier , Mesa Jordi

Introduction: Classically, risk stratification in papillary thyroid carcinoma (PTC) assigned the same magnitude of risk to all patients with regional lymph node involvement (N1 disease). However, specific lymph node characteristics (such as size, number, extension, etc.) will allow individualizing treatment and follow-up. One-Step Nucleic Acid Amplification (OSNA) measures the number of copies of mRNA of cytokeratin 19 (CK19) as a marker of lymph node metastasis. Thus, copy nu...

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ePoster

ea0037gp.24.04 | Thyroid–genetics | ECE2015

Lymph node involvement using one-step nucleic acid amplification according to BRAF gene mutation status in patients with papillary thyroid carcinoma submitted to lymph node dissection

Zafon Carles , Gonzalez Oscar , Temprana Jordi , Obiols Gabriel , Garcia-Burillo Amparo , Serres Xavier , Balibrea Jose Maria , Castell Joan , Mesa Jordi , Iglesias Carmela

Introduction: The relationship between the BRAF gene mutation in papillary thyroid cancer (PTC) and the presence of lymph node metastasis (LNM) is a subject of controversy.Objective: To analyse the influence of BRAF mutation status in the characteristics of lymph nodes in patients with PTC submitted to lymph node dissection (LND).Material and methods: Lymph nodes obtained from 20 patients (12 females, mean age 50±15 y...

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ePoster

Endocrine Abstracts

Macro, but not micrometastases, detected by OSNA technique are related with more aggressive papillary thyroid cancer features

Lymph node involvement using one-step nucleic acid amplification according to BRAF gene mutation status in patients with papillary thyroid carcinoma submitted to lymph node dissection

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